An ancient enemy of mean disposition (6)
I believe the answer is:
foeman
'an ancient enemy' is the definition.
'foeman' can be an answer for 'enemy' (I've seen this in another clue). I am not certain of the 'an ancient' bit.
'of mean disposition' is the wordplay.
'disposition' indicates anagramming the letters.
'of'+'mean'='ofmean'
'ofmean' anagrammed gives 'FOEMAN'.
Can you help me to learn more?
(Other definitions for foeman that I've seen before include "Enemy in war" , "Archaic male enemy" .)