An article against setter? It takes your breath away (8)
I believe the answer is:
anaconda
'it takes your breath away' is the definition.
The definition suggests a singular noun which matches the answer.
'an article against setter?' is the wordplay.
I cannot really understand how this works, but
'an' could be 'a' and 'a' is located in the answer.
'article' could be 'a' (the indefinite article in English) and 'a' is found in the answer.
'against' could be 'on' (I've seen this in other clues) and 'on' is found in the answer.
This may be the basis of clue (or it may be nonsense).
Can you help me to learn more?
(Other definitions for anaconda that I've seen before include "Water-boa" , "Huge South American snake" , "Semi-aquatic boa" , "'No, Canada is home to the snake (8)'" , "Large South America snake" .)