An increase once more (5)
I believe the answer is:
again
'once more' is the definition.
(synonyms)
'an increase' is the wordplay.
'an' becomes 'a'.
'increase' becomes 'gain' (gaining is a kind of increasing).
'a'+'gain'='AGAIN'
(Other definitions for again that I've seen before include "10 10 [AGAIN" , "Furthermore" , "repeat order" , "Not for the first time" , "One more time, encore" .)