An insect on the move, most cautious (8)
I believe the answer is:
canniest
'most cautious' is the definition.
Both the answer and definition are superlative adjectives. Perhaps you can see a link between them that I can't see?
'an insect on the move' is the wordplay.
'on the move' indicates an anagram.
'an'+'insect'='aninsect'
'aninsect' anagrammed gives 'CANNIEST'.
Can you help me to learn more?
(Other definitions for canniest that I've seen before include "Shrewdest sort of ancients" , "Instance (anag)" .)