An out-of-the-way route (5)
I believe the answer is:
outre
'an out-of-the-way' is the definition.
(thesaurus)
'route' is the wordplay.
'route' anagrams to 'OUTRE'.
Though, I am not sure how the anagram is indicated.
Can you help me to learn more?
(Other definitions for outre that I've seen before include "Shocking - route (anag)" , "Exotic" , "Remarkable" , "Going too far" , "Eccentric, improper" .)