Anaesthetic used there (5)
I believe the answer is:
ether
'anaesthetic' is the definition.
(ether is a kind of anaesthetic)
'used there' is the wordplay.
'used' indicates anagramming the letters.
'there' is an anagram of 'ETHER'.
(Other definitions for ether that I've seen before include "Former anaesthetic" , "Rare atmosphere" , "Chemical solvent" , "Type of chemical" , "Some were put out by this" .)