Anatomically, it's different from the elbow (5)
I believe the answer is:
bowel
'anatomically it's different' is the definition.
I can't judge whether this definition defines the answer.
'from the elbow' is the wordplay.
'from' indicates anagramming the letters (from the letters).
'elbow' is an anagram of 'BOWEL'.
Can you help me to learn more?
(Other definitions for bowel that I've seen before include "Large intestine" , "Gut" , "part of canal" .)