Ancient Nile region (5)
I believe the answer is:
nubia
'ancient nile region' is the definition.
(I've seen this before)
This is the entire clue.
(Other definitions for nubia that I've seen before include "Region of northeast Africa" , "Ancient Nile region" , "Ancient African country in Egypt and Sudan" , "Upper 16 Across region" , "African kingdom" .)