...and I'm sure to upset nanny (9)
I believe the answer is:
nursemaid
'nanny' is the definition.
(both can mean someone who looks after children)
'and i'm sure to upset' is the wordplay.
'to upset' is an anagram indicator.
'and'+'im'+'sure'='andimsure'
'andimsure' with letters rearranged gives 'NURSEMAID'.
(Other definitions for nursemaid that I've seen before include "Girl tending young children" , "Be overprotective towards (someone)" , "Woman employed to look after children" , "female carer" , "her charges are small" .)