"And Then There Were None” director Clair (4)
I believe the answer is:
rene
'and then there were none director clair' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for rene that I've seen before include "- Lalique, glass artist" , "- Descartes, French mathematician" , "-- Magritte, artist" .)