Anger in rural establishments — they may kill people (8)
I believe the answer is:
firearms
'they may kill people' is the definition.
'anger in rural establishments' is the wordplay.
'anger' becomes 'ire' ('ire' can be a synonym of 'anger').
'in' indicates putting letters inside.
'rural establishments' becomes 'farms'.
'ire' placed into 'farms' is 'FIREARMS'.
(Other definitions for firearms that I've seen before include "they can kill people" , "Rifles, guns, pistols etc" , "Weaponry" , "Portable guns" , "Weapons" .)