Angry about female despoiled (6)
I believe the answer is:
rifled
'despoiled' is the definition.
('rifle' can be a synonym of 'despoil')
'angry about female' is the wordplay.
'angry' becomes 'riled' (I've seen this before**).
'about' means one lot of letters goes inside another.
'female' becomes 'f' (abbreviation).
'riled' placed around 'f' is 'RIFLED'.
(Other definitions for rifled that I've seen before include "Ransacked" , "Searched through" .)