Animal from the east in Wild Wales (6)
I believe the answer is:
weasel
'animal' is the definition.
(I've seen this before)
'east in wild wales' is the wordplay.
'east' becomes 'e' (abbreviation).
'in' is an insertion indicator.
'wild' indicates anagramming the letters.
'wales' with letters rearranged gives 'weasl'.
'e' placed inside 'weasl' is 'WEASEL'.
'from the' acts as a link.
(Other definitions for weasel that I've seen before include "Sly character" , "Carnivore -- saw eel (anag)" , "One deceiving" , "Old jingle 'Pop goes the . . . . . .'" , "Stoat-like animal" .)