Animals heading away a tad agitated, they're naturally spotted (10)
I believe the answer is:
dalmatians
'they're naturally spotted' is the definition.
'animals heading away a tad agitated' is the wordplay.
'heading away' means to remove the first letter.
'agitated' indicates anagramming the letters.
'animals' with its first letter taken away is 'nimals'.
'nimals'+'a'+'tad'='nimalsatad'
'nimalsatad' with letters rearranged gives 'DALMATIANS'.
I've seen this clue in The Independent.
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