Anne is flipping mad (6)
I believe the answer is:
insane
'mad' is the definition.
(I know that mad can be written as insane)
'anne is flipping' is the wordplay.
'flipping' is an anagram indicator (I've seen 'flips' mean this).
'anne'+'is'='anneis'
'anneis' is an anagram of 'INSANE'.
(Other definitions for insane that I've seen before include "out to lunch" , "without any reason" , "Anne is (anag) - crazy" , "mad for love?" , "Quite mad" .)