Anne is so unbalanced (6)

I believe the answer is:

insane

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'unbalanced' is the definition.
(similar in meaning)

'anne is' is the wordplay.
'anne is' can be anagrammed to 'INSANE'.
Though, I am not clear how this is indicated.

'so' is the link.

Can you help me to learn more?

(Other definitions for insane that I've seen before include "Irresponsible" , "mad for love?" , "nuts" , "Round the bend" , "Quite mad" .)

I've seen this clue in The Globe and Mail.

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