Annoy a lot (6)
(Other definitions for rankle that I've seen before include "Cause ill-feeling" , "Annoy continually" , "Eat into and cause resentment" , "Continue to vex" , "Fester" .)
I've seen this clue in the King Feature Syndicate, the Newsday.com and the Newsday.
I've seen this clue in the Newsday.
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