Annoy or anger (8)
I believe the answer is:
irritate
I believe this clue is a double definition.
'annoy' is the first definition.
(I know that annoy can be written as irritate)
'anger' is the second definition.
(thesaurus)
(Other definitions for irritate that I've seen before include "bug" , "Vex, aggravate" , "Wind up" , "Anger, annoy" , "Nark" .)