Annoy with something sharp (6)
I believe the answer is:
needle
'annoy' is the definition.
(needle can mean to annoy or irritate)
I don't understand the remainder of the clue.
Can you help me to learn more?
(Other definitions for needle that I've seen before include "Annoy by continuous criticism; stylus" , "Irritate or provoke with sewing implement" , "Injection" , "It's vital to baste" , "Irritate with knitting implement" .)