Annoyance. vexation (7)

I believe the answer is:

chagrin

(Other definitions for chagrin that I've seen before include "Humiliation, mortification" , "Arching with annoyed disappointment" , "Discomfiture" , "Feeling of annoyance and disappointment" , "Acute annoyance or disappointment" .)

I've seen this clue in The Guardian.

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