Annoyed, irritated (5)
I believe the answer is:
irked
This clue is a double definition.
'annoyed' is the first definition.
(I've seen this in another clue)
'irritated' is the second definition.
(I've seen this in another clue)
(Other definitions for irked that I've seen before include "Irritated - bothered" , "Vexed, annoyed" , "disgusted" , "Bugged" , "Irritated, vexed" .)