Answer again with strand of yarn (5)
I believe the answer is:
reply
'answer again' is the definition.
(I know that answer is a type of reply)
'strand of yarn' is the wordplay.
I cannot quite see how this works, but
'strand' could be 'ply' (ply is a kind of strand) and 'ply' is found in the answer.
The remaining letters 're' is a valid word which might be clued in a way I don't understand.
This explanation may well be incorrect...
'with' is the link.
Can you help me to learn more?
(Other definitions for reply that I've seen before include "Returned statement" , "counterattack?" , "Answer, respond" , "Return" , "acknowledgement" .)