Answer is again wrong (6)
I believe the answer is:
retort
'answer' is the definition.
(I know that retort is a type of answer)
'again wrong' is the wordplay.
'again' becomes 're' (prefix meaning 'again').
'wrong' becomes 'tort' (a civil wrong in law).
're'+'tort'='RETORT'
'is' acts as a link.
(Other definitions for retort that I've seen before include "Rotter (anag.)" , "Lab. vessel; quip" , "A quick, sharp reply" , "Answer in retaliation" , "Witty/sharp reply" .)