Anybody over at Mile End (3)
I believe the answer is:
'anybody' is the definition.
(I've seen this in another clue)
'over at mile end' is the wordplay.
'over' becomes 'on' (physically on top of).
'at' says to put letters next to each other.
'end' suggests the final letters.
The last letter of 'mile' is 'e'.
(Other definitions for one that I've seen before include "Individual" , "A certain; single person" , "United" , "Single, sole" , "1" .)