Anyone with them has a strong impulse to travel (5,4)
I believe the answer is:
itchy feet
(Other definitions for itchy feet that I've seen before include "Strong desire to travel" , "reason for leaving?" , "Have . . . . . . . . . with restless desire to travel" , "They show a strong urge to travel" , "Restlessness, a desire to travel - or scratch?" .)