Are led astray by the one in charge (6)
I believe the answer is:
leader
'the one in charge' is the definition.
(a leader is in charge)
'are led astray' is the wordplay.
'astray' is an anagram indicator.
'are'+'led'='areled'
'areled' anagrammed gives 'LEADER'.
'by' acts as a link.
(Other definitions for leader that I've seen before include "One is ahead and shows the way" , "Editorial - chief" , "Important (newspaper) article" , "One whose example is followed" , "Pioneer" .)