Arrangement for piano and sitar? Some hope (10)
I believe the answer is:
aspiration
'some hope' is the definition.
(I've seen this before)
'arrangement for piano and sitar?' is the wordplay.
'arrangement for' is an anagram indicator (I've seen this in other clues).
'and' is a charade indicator (letters next to each other).
'piano'+'sitar'='pianositar'
'pianositar' with letters rearranged gives 'ASPIRATION'.
(Other definitions for aspiration that I've seen before include "Ambition" , "Eager desire" , "Craving" , "Hope" , "Drawing breath" .)