Arrival into major road bound to result in an accident (12)
I believe the answer is:
misadventure
'in an accident' is the definition.
'misadventure' can be an answer for 'accident' (misadventure is a kind of accident). I am unsure of the 'in an' bit.
'arrival into major road bound to' is the wordplay.
'arrival' becomes 'advent' (advent is a kind of arrival).
'into' is an insertion indicator.
'major road' becomes 'MI' (resembles M1, English motorway).
'bound to' becomes 'sure' (synonyms).
'mi'+'sure'='misure'
'advent' put inside 'misure' is 'MISADVENTURE'.
'result' is the link.
Can you help me to learn more?
(Other definitions for misadventure that I've seen before include "disaster" , "Mishap" , "Accident" , "Unfortunate incident" , "Bad luck; accidental killing" .)