Artist establishes gambling location on outskirts of Izmir (6)
I believe the answer is:
renoir
'artist' is the definition.
(French artist Pierre-Auguste Renoir)
'gambling location on outskirts of izmir' is the wordplay.
'gambling location on' becomes 'reno' (I can't explain this - if you can you should give a lot more credence to this answer).
'outskirts of' says to hollow out the word (remove centre letters) (only letters on the outskirts).
'izmir' with its centre taken out is 'ir'.
'reno'+'ir'='RENOIR'
'establishes' is the link.
Can you help me to learn more?
(Other definitions for renoir that I've seen before include "'No, I err, he was a painter (6)'" , "French artist" , "Pierre-Auguste -, French Impressionist painter" , "Pierre Auguste ---, painter; Jean ---, film-director" , "Pierre ---, impressionist" .)