Artwork made by a couple of Greek characters (5)
I believe the answer is:
pieta
'couple of greek characters' is the definition.
Although both the answer and definition are singular nouns, I cannot see how they can define each other.
'artwork made by a' is the wordplay.
I cannot quite see how this works, but
'a' is present in the answer.
The remaining letters 'piet' is a valid word which might be clued in a way I don't see.
This explanation may well be incorrect...
Can you help me to learn more?
(Other definitions for pieta that I've seen before include "(In painting etc) representation of the dead Christ" , "Statue of Mary with the dead Christ" , "Statue of Virgin Mary" , "Religious work resulting" , "Statue of Mary with body of Jesus" .)