As little house with good bit of seafood (6)
I believe the answer is:
quahog
'seafood' is the definition.
(quahog is a kind of seafood)
'as little house with good bit of' is the wordplay.
'as' becomes 'qua' ('qua' is a Latin term meaning 'in the capacity of').
'little house' becomes 'ho' (abbreviation for house. I am not sure about the 'little' bit.).
'with' means one lot of letters go next to another.
'bit of' indicates taking the first letters.
The initial letter of 'good' is 'g'.
'qua'+'ho'+'g'='QUAHOG'
Can you help me to learn more?
(Other definitions for quahog that I've seen before include "Round clam" , "North American edible clam" .)