Assumption in force inspiring me after uprising (7)
I believe the answer is:
premise
'assumption' is the definition.
('premise' can be a synonym of 'assumption')
'force inspiring me after uprising' is the wordplay.
'force' becomes 'prise' (I've seen this before**).
'inspiring' is an insertion indicator.
'after uprising' says the letters should be written in reverse.
'me' written backwards gives 'em'.
'prise' going around 'em' is 'PREMISE'.
'in' is the link.
(Other definitions for premise that I've seen before include "argument" , "Basis of theory" , "Underlying assumption" , "Hypothesis" , "Statement on which reasoning is based" .)