At home, anxious and extreme (7)
I believe the answer is:
intense
'extreme' is the definition.
(similar in meaning)
'at home anxious' is the wordplay.
'at home' becomes 'in' ('I'm in' can mean 'I'm at home').
'anxious' becomes 'tense' (I've seen this before).
'in'+'tense'='INTENSE'
'and' acts as a link.
(Other definitions for intense that I've seen before include "Strongly-felt" , "Deeply felt or vehement" , "Extremely emotional" , "Excited" , "Of extreme force" .)