At home Chubby nurses new baby (6)
I believe the answer is:
infant
'baby' is the definition.
(I know that baby can be written as infant)
'at home chubby nurses new' is the wordplay.
'at home' becomes 'in' (similar in meaning).
'chubby' becomes 'fat' (similar in meaning).
'nurses' means one lot of letters goes inside another (nurse can mean to hold onto or harbour).
'new' becomes 'n' (common abbreviation eg NT for New Testament).
'fat' going around 'n' is 'fant'.
'in'+'fant'='INFANT'
(Other definitions for infant that I've seen before include "Small boy" , "Small baby" , "Juvenile" , "Thing in early stage; minor (legal)" , "Child at an early stage of life" .)