At home opening wine, a pipe (8)
I believe the answer is:
clarinet
'a pipe' is the definition.
(thesaurus)
'at home opening wine' is the wordplay.
'at home' becomes 'in' ('I'm in' can mean 'I'm at home').
'opening' indicates putting letters inside (some letters open a gap in others).
'wine' becomes 'claret' (claret is a kind of wine).
'in' inserted inside 'claret' is 'CLARINET'.
(Other definitions for clarinet that I've seen before include "Single reed woodwind instrument" , "Woodwind instrument - Artie Shaw played one" , "member of orchestra" , "23 instrument" , "Instrument in claret, strangely" .)