At home with Brazilian money -- pity penny's missing, actually (2,7)
I believe the answer is:
in reality
'actually' is the definition.
(synonyms)
'at home with brazilian money pity penny's missing' is the wordplay.
'at home' becomes 'in' ('I'm in' can mean 'I'm at home').
'with' says to put letters next to each other.
'brazilian money' becomes 'real' (currency of Brazil).
'penny' becomes 'p' (short for pence).
'missing' indicates named letters should be taken away.
'pity' with 'p' removed is 'ity'.
'in'+'real'+'ity'='IN REALITY'
(Another definition for in reality that I've seen is " As a matter of fact".)