Audible cry from large creature (5)
I believe the answer is:
whale
'large creature' is the definition.
(I've seen this before)
'audible cry' is the wordplay.
'audible' shows a homophone (sound like).
'cry' becomes 'wail' (wailing is a kind of crying).
'wail' is a homophone of 'WHALE'.
'from' is the link.
(Other definitions for whale that I've seen before include "Large marine mammal" , "Maybe humpback" , "Great sea mammal" , "Aquatic mammal" , "Leviathan" .)