Avoid commercial accepted by the first woman (5)
I believe the answer is:
evade
'avoid' is the definition.
(I know that evade is a more specific form of the action avoid)
'commercial accepted by the first woman' is the wordplay.
'commercial' becomes 'ad' (abbreviation for advertisement).
'accepted by' indicates putting letters inside (inserted letters are accepted).
'the first woman' becomes 'eve' (first woman in the bible).
'ad' inserted inside 'eve' is 'EVADE'.
(Other definitions for evade that I've seen before include "Shirk" , "Dodge, duck" , "Dodge or equivocate" , "Shun, escape" , "temptress conveying commercial message" .)