Aware of company boss trapped at home with dreadful flu (7)
I believe the answer is:
mindful
'aware of' is the definition.
(thesaurus)
'company boss trapped at home with dreadful flu' is the wordplay.
'company boss' becomes 'md' (Managing Director).
'trapped' indicates putting letters inside.
'at home' becomes 'in' ('in' can be similar in meaning to 'at home').
'with' means one lot of letters go next to another.
'dreadful' indicates anagramming the letters.
'md' enclosing 'in' is 'mind'.
'flu' with letters rearranged gives 'ful'.
'mind'+'ful'='MINDFUL'
(Other definitions for mindful that I've seen before include "Taking heed" , "Conscious (of); remembering" , "Aware (of something)" , "Aware and cognizant" , "Taking care" .)