Awful man with the writer? On the contrary, you and me (7)
I believe the answer is:
heinous
'awful' is the definition.
(I've seen this before)
'man with the writer? on the contrary you and me' is the wordplay.
'man' becomes 'he' (pronoun for a man).
'with' means one lot of letters go next to another.
'the writer?' becomes 'I' (the person who is writing these clues).
'the contrary' says the letters should be written in reverse.
'you and me' becomes 'us'.
'on' reversed gives 'no'.
'he'+'i'+'no'+'us'='HEINOUS'
(Other definitions for heinous that I've seen before include "Hateful" , "Utterly wicked" , "Shockingly wicked" , "Very wicked, maybe in-house" , "Execrable" .)