Awfully primitive nurses roughly following Florence's lead (10)

'awfully' is the definition.
(awful can mean fearsome)

'primitive nurses roughly following florence's lead' is the wordplay.
I cannot really understand how this works, but
'roughly' could be 'some' ('some' said before a number means 'roughly') and 'some' is found in the answer.
'primitive' could be 'early' (similar in meaning) and 'early' is found in the remaining letters.
'following' could be 'f' (used when citing page numbers etc) and 'f' is present in the answer.
No letters remain.
This may be the basis of clue (or it may be nonsense).