Basically at home with perfume (2,7)
I believe the answer is:
in essence
'basically' is the definition.
(synonyms)
'home with perfume' is the wordplay.
'home' becomes 'in' ('he's home' can mean 'he's in').
'with' is a charade indicator (letters next to each other).
'perfume' becomes 'essence' (synonyms).
'in'+'essence'='IN ESSENCE'
'at' is the link.
(Other definitions for in essence that I've seen before include "at bottom" , "Basically" , "Substantially" , "Fundamentally" .)