Be in charge and live under pressure (7)
I believe the answer is:
preside
'be in charge' is the definition.
(I've seen this in another clue)
'live under pressure' is the wordplay.
'live' becomes 'reside' (synonyms).
'under' is a charade indicator (letters next to each other) (in a down clue, some letters go below others).
'pressure' becomes 'p' (abbreviation).
'reside' after 'p' is 'PRESIDE'.
'and' is the link.
(Other definitions for preside that I've seen before include "Take the chair" , "Be chairman" , "Be in authority (over)" .)