Be overwhelmed with new information from the east (5)
I believe the answer is:
drown
'be overwhelmed' is the definition.
(I've seen this in another clue)
'with new information from the east' is the wordplay.
'with' says to put letters next to each other.
'new' becomes 'n' (common abbreviation eg NT for New Testament).
'information' becomes 'word' (word is a kind of information).
'from the east' says the letters should be written in reverse (on a map from right to left).
'n' put next to 'word' is 'nword'.
'nword' back-to-front is 'DROWN'.
(Other definitions for drown that I've seen before include "Kill by submersion" , "Go under" , "Die by inhaling liquid" , "Perish in water" , "Become submerged" .)