Be overwhelmed with new information from the east (5)
I believe the answer is:
drown
'be overwhelmed' is the definition.
(I've seen this in another clue)
'with new information from the east' is the wordplay.
'with' is a charade indicator (letters next to each other).
'new' becomes 'n' (abbreviation as in New Testament NT).
'information' becomes 'word' (word is a kind of information).
'from the east' says the letters should be written backwards (on a map from right to left).
'n' put next to 'word' is 'nword'.
'nword' backwards is 'DROWN'.
(Other definitions for drown that I've seen before include "Kill by submersion" , "Go under" , "Die by inhaling liquid" , "Perish in water" , "Become submerged" .)