Crossword Genius

Be sick of entertaining the Spanish premier's wife (8)

Ross

I believe the answer is:

helpmate

'wife' is the definition.
(thesaurus)

'be sick of entertaining the spanish premier's' is the wordplay.
'be sick of' becomes 'hate'.
'entertaining' indicates putting letters inside.
'the spanish' becomes 'el'.
'premier' becomes 'pm' ('PM' can be a synonym of 'premier').
'el'+'pm'='elpm'
'hate' placed around 'elpm' is 'HELPMATE'.

(Another definition for helpmate that I've seen is " Partner".)

I've seen this clue in The Times.
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