Bear, little one, last of three (4)
I believe the answer is:
tote
'bear' is the definition.
(thesaurus)
'little one last of three' is the wordplay.
'little one' becomes 'tot'.
'last of' suggests the final letters.
The last letter of 'three' is 'e'.
'tot'+'e'='TOTE'
(Other definitions for tote that I've seen before include "Haul, carry" , "system that could be for the better" , "system for betters" , "Large bag" , "Transfer" .)