Bearing the burden, couldn't stand (7)
I believe the answer is:
loathed
'couldn't stand' is the definition.
(I've seen this in another clue)
'bearing the burden' is the wordplay.
'bearing' is an insertion indicator.
'burden' becomes 'load' (synonyms).
'the' inserted inside 'load' is 'LOATHED'.
(Other definitions for loathed that I've seen before include "Hated" , "'Abhorred, detested (7)'" , "Regarded with disgust and hatred" , "Cordially detested" , "Detested and abominated" .)