Beast wandering in Cuba and Rio (7)
I believe the answer is:
caribou
'beast' is the definition.
'wandering in cuba and rio' is the wordplay.
'wandering in' is an anagram indicator (I've seen this in other clues).
'and' is a charade indicator (letters next to each other).
'cuba' put after 'rio' is 'riocuba'.
'riocuba' is an anagram of 'CARIBOU'.
(Other definitions for caribou that I've seen before include "Wild animal" , "Arctic deer - a Rio cub (anag)" , "Ruminant" , "N.American reindeer" , "North American reindeer" .)