Because wickedness ends in disgrace? (5)
I believe the answer is:
since
'because' is the definition.
(I've seen this in another clue)
'wickedness ends in disgrace?' is the wordplay.
'wickedness' becomes 'sin' (synonyms).
'ends in disgrace?' becomes 'ce' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'sin'+'ce'='SINCE'
Can you help me to learn more?
(Other definitions for since that I've seen before include "Because; ago" , "in the past" , "From that time one" , "Seeing that" .)