Beginning once more, we learn to be different (7)
I believe the answer is:
renewal
'beginning once more' is the definition.
'renewal' can be an answer for 'beginning' (I have seen 'Fresh beginning' mean 'renewal' so perhaps 'beginning' could also mean 'renewal'). I'm not sure about the 'once more' bit.
'we learn to be different' is the wordplay.
'to be different' is an anagram indicator (I've seen 'is different' mean this).
'we'+'learn'='welearn'
'welearn' with letters rearranged gives 'RENEWAL'.
Can you help me to learn more?
(Other definitions for renewal that I've seen before include "Revitalisation" , "Renovation; resumption" , "fresh start" , "what happens in a library" , "Act of refreshing" .)